2. Vías de señalización
  3. GPCR/G Protein
  4. Bradykinin Receptor
  5. Bradykinin B2 Receptor (B2R) Isoform
  6. Bradykinin B2 Receptor (B2R) Agonist

Bradykinin B2 Receptor (B2R) Agonist

Bradykinin B2 Receptor (B2R) Agonists (3):

Cat. No. Nombre del producto Efecto Pureza
  • HY-105155
    Lobradimil
    		Agonist 99.76%
    Lobradimil (RMP 7), a synthetic bradykinin analog, is a potent and selective bradykinin B2 receptor agonist (Ki: 0.54 nM). Lobradimil increases the permeability of the BBB. Lobradimil can be used in the research of brain tumors.
  • HY-118945
    FR191413
    		Agonist
    FR191413 is a selective bradykinin B2 receptor agonist that stimulates prostaglandin E2 production in WI-38 cells and activates BK B2 receptor-mediated pathways such as vasodilation and organ protection. FR191413 competitively binds to [3H]-BK in guinea pig ileum (GPI) membranes and CHO cells transfected with the human BK B2 receptor, with IC50 values ​​of 20.0 nM and 2.60 nM, respectively. FR191413 can be used in research related to cardiovascular diseases and diabetes, including hypertension, myocardial hypertrophy, myocardial infarction, arrhythmias, and diabetic nephropathy.
  • HY-123376
    FR-190997
    		Agonist
    FR-190997 is a non-peptide Bradykinin B2 receptor selective agonist, Ki value is 9.8 nM. FR-190997 is also an effective antihypertensive agent.